I've often wondered this. There came a brief period where he tried to move away from playing bad guys, and played good guys, which didn't always fit him quite as well. Plus to some extent, Rutger is actually too interesting an actor to be a lead, or to be mainstream. It's why he never really broke out as a leading man. He's better in supporting roles, or as antagonists.
But I'm with you, Blade Runner is my favourite film. Rutgers still one of my favourite actors. Despite the way his career went, he's almost always reliable, even in bad movies. He's known for being unpredictable on set too. Which might have put some people off too.